Year: 2018 | Month: April | Volume 8 | Issue 2
Effect of Vitamin C on Some Oxidative Stress Parameters in Water Deprived Goats
Abstract:
The effect of vitamin C on physio-biochemical and hormonal parameters in water deprived goats was studied. Total 18 numbers of adult male goats were selected for the experiment during summer and winter seasons. In control group (n=6, for each season), water was offered ad lib throughout the experimental period; 2 treatment groups (T1 and T2) consisting of 6 animals each. In T1 group, water was restricted and subdivided into 3 experimental periods: in period one (day 1 to 7), animals were adapted to the water restriction regime by limiting access to water gradually from 15 to 3 hrs/day. In period two (day 8 to 14), animals of the treatment groups had access to water for 3 hrs/day. In period three (day 15 to 22), animals had access to water only every second day for 6 hours. In T2 group, the same protocol as mentioned above was followed with addition of vitamin C supplementation at a dose rate of 180 mg/kg b. wt./animal/day. Blood and urine was collected on 1, 7, 14 and 22 day for the estimation of different parameters. In T1 group, increasing trend (P<0.05) was seen in SOD, GPx, GST, catalase and LPO in blood. In T2 group, SOD, GPx, catalase and LPO levels increased upto day 14 and then decreased on day 22. T1 value of oxidative enzymes (SOD, GPx, GST, catalase and LPO) was significantly higher (P<0.05) than T2. Overall summer value of SOD, GPx and LPO were higher as compared to overall winter values.Water deprivation had negative impact on oxidative parameters, which can be ameoliorated by supplementation of ascorbic acid at the rate of @180mg/kg b.wt./day.
© This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Print This Article Email This Article to Your Friend
